What if there were a straightforward and relatively inexpensive way to lower the incidence of heart failure (HF), renal disease, stroke, and cognitive impairment? Cardiologist Bertram Pitt, MD, said ...

One of the functions of your adrenal glands is to produce a hormone called aldosterone that plays an active role in your blood pressure. It does this by maintaining the balance of sodium, potassium, ...

Hyperaldosteronism is when one or both adrenal glands release too much of the hormone aldosterone. High blood pressure can result, which could lead to atrial fibrillation, heart attack, or stroke.

Aldosterone synthase controls the synthesis of aldosterone and has been a pharmacologic target for the treatment of hypertension for several decades. Selective inhibition of aldosterone synthase is ...