The cell body of an injured neuron must receive accurate and timely information about axonal damage to reproduce polarization. It has been widely recognized that a dendrite is transformed into a new ...

Injury of CNS nerve tracts remodels circuitry through dendritic spine loss and hyper-excitability, thus influencing recovery. Due to the complexity of the CNS, a mechanistic understanding of ...

In one of the very early examples of activity dependent gene expression, we showed that stimulation of the cervical sympathetic trunk led to an increase in the activity of protein level, and mRNA ...

Among all the bad things that can happen to the brain when it is severely jolted - in a car accident, for example - one of the most common and worrisome is axon damage. Axons are the long stalks that ...