New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...

Cell surface interactions and receptor dynamics underpin every stage of immune function, from antigen recognition to effector responses. At the plasma membrane, receptors such as the T cell receptor ...

Cells have surface receptors that couple to proteins and other molecules to initiate or inhibit certain behaviors.

Receptor clustering mediated by antigen or ligand binding represents a general mechanism that underlies the activation of diverse cell surface receptors, including T cell receptors (TCRs), B cell ...