Although only 1.5% of the human genome appears to code for proteins, much effort in cancer research has been devoted to this minimal fraction of our DNA. However, the last few years have witnessed the ...

The Testisin gene (PRSS21) encodes a glycosylphosphatidylinositol (GPI)-linked serine protease that exhibits testis tissue-specific expression. Loss of Testisin has been implicated in testicular ...

'CpG islands' are often associated with promoter regions. A CpG island has traditionally been defined as a 200 bp region of DNA with a G+C content over 50% and an observed/expected CpG ratio of 0.6 or ...

A team of researchers from the Davis Center for Regenerative Biology and Medicine, MDI Biological Laboratory, the University of Texas at Austin and the Jackson Laboratory has found evidence that gene ...

Association of hypermethylation at the NDRG4 CpG island with the risk of gastric cancer. This is an ASCO Meeting Abstract from the 2016 ASCO Annual Meeting I. This abstract does not include a full ...

Mouse prostate tumor inhibition via disruption of murine telomerase: In vivo and in vitro data for a new preclinical cancer model No significant financial relationships to disclose. This is an ASCO ...

(HealthDay)—For patients undergoing colorectal cancer (CRC) surgery, CpG island methylator phenotype (CIMP) status predicts survival, according to research published online Jan. 14 in the Journal of ...

Aging being the biggest risk factor for neurodegenerative disease, scientists urgently want to know what exactly goes wrong in old cells. In the December 15 Science Advances, researchers led by Samuel ...