The dentate gyrus (DG) is a region of the mammalian brain known to support the encoding of new memories. This brain region is part of the hippocampal formation, a set of brain regions involved in ...
To see if the dentate gyrus is the source of age-related memory decline in humans, Dr. Small and his colleagues tested whether compounds called cocoa flavanols can improve the function of this brain ...
Left: In the dentate gyrus of the hippocampus of 4-5 month-old Rp58 heterozygous-KO mice, DNA damage accumulates in the mossy cells (yellow-green) (ssDNA; red), and the surrounding microglia (blue) ...
Age-related memory decline may be reversed with high doses of naturally occurring cocoa flavanols, US researchers have discovered in findings that establish the dentate gyrus as central to cognitive ...
In the process of solving a decades-long mystery about a particular protein, scientists have identified a specific location in the brain where schizophrenia may originate. The news: Despite the ...
Researchers present data and a simple statistical network model that describe an unanticipated property of newly formed, immature neurons in the dentate gyrus. The model resolves a seeming paradox in ...
Dietary cocoa flavanols—naturally occurring bioactives found in cocoa—reversed age-related memory decline in healthy older adults, according to a study led by Columbia University Medical Center (CUMC) ...
It appears that new cells compete to ‘win’ synapse connections away from old cells, which promotes network plasticity. Linda Overstreet-Wadiche, Ph.D. One goal in neurobiology is to understand how the ...
A specific location in the brain where schizophrenia may originate has been identified by scientists in the process of solving a decades-long mystery about a particular protein. Despite identifying ...