Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression.

A group of more than 50 experts in the field of pancreatic islet cell transplantation is calling for reclassification of the type 1 diabetes therapy from biologic drug to human organ. The treatment ...

Over 500 million people worldwide suffer from diabetes—a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer’s disease. At the heart of this condition ...

In 1993 the Diabetes Control and Complications Trial (DCCT) established the modern standard of care for the medical management of type 1 diabetes mellitus. 1 The DCCT randomly assigned 1441 patients ...

A team of international scientists has made a major leap forward in diabetes research by successfully 3D printing functional human islets using a novel bioink (Monday, 30 June 2025, London, United ...

The currently approved islet-transplant method infuses islets into a vein in the liver. This invasive procedure requires the long-term use of immune-suppressing drugs to prevent islet rejection, ...

ProtoKinetix has announced the start of a phase 1 first-in-human clinical trial of AAGP PKX-001 treated islet cells used in conjunction with the Edmonton Protocol for the treatment of Type 1 diabetes.

Affecting more than 500 million people worldwide, diabetes mellitus is a growing burden to patients' longevity and quality of life, as well as an increasing challenge to health care systems. The ...

Detailed characterization of human pancreatic islets is key to elucidate the pathophysiology of all forms of diabetes mellitus, including its most common form known as type 2 diabetes (T2D). However, ...