Scleroderma is a rare autoimmune disease involving an overproduction of the protein collagen. Linear scleroderma usually begins as a streak of hardened, waxy, discolored skin on the forehead, an arm, ...

Systemic sclerosis (scleroderma) causes the body to destroy healthy tissue. It can change the appearance and texture of your skin and affect other organs. Systemic sclerosis (SS) is an autoimmune ...

Localized scleroderma, as the term denotes, is localized to the skin on the hands and face. It is characterized by slow progression and rarely transforms to the systemic type. Localized scleroderma is ...

Scleroderma, also sometimes referred to as systemic sclerosis, is a chronic autoimmune disorder that involves a progressive hardening of the skin. An excess of collagen and other connective tissues in ...

Scleroderma is an autoimmune condition that causes the skin to become tight and hard. This can change facial appearance, such as the mouth becoming smaller, and affect internal organs. With ...

The management of patients with systemic sclerosis (SSc) can be challenging because disease-associated damage is often difficult to reverse and curative therapies are not yet available. Early ...

Most people with scleroderma have autoantibodies. Several scleroderma-specific antibodies have been identified. These can help with diagnosis and give insight into the type of disease you may ...

Scleroderma survivor, Susan Spence-Le Gendre has been battling the life-threatening condition for over a decade. The discomfort never stops pain, fatigue, weakness, aching muscles, joints and bones, ...